Effects of 5-(3-tert-butylamino-2-hydroxy) propoxy-3, 4-dihydrocarbostyril hydrochloride (OPC-1085), a new beta-adrenergic blocking agent on the coronary circulation and myocardial metabolism
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منابع مشابه
Antiarrhythmic Activity of Dextro and Levo Isomers of 5-methyl-8-(2-hydroxy-3-t-butylamino Propoxy) Coumarin Hydrochloride (bucumolol), a 18-adrenergic Blocking Agent, on Aconitine Induced Atrial and Ouabain-induced Ventricular Arrhythmias in Dogs
The (3-blocking, antiarrhythmic, and local anesthetic effects of the racemic mixture and optical isomers of bucumolol, 5-methyl-8-(2-hydroxy-3-t-butylamino propoxy) coumarin hydrochloride, were studied in dogs, guinea-pigs and frogs. In blocking the positive chronotropic response to isoproterenol, the levo-isomer of bucumolol was about 40 times more potent in dogs, and 270 times in guinea-pigs ...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 1975
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.71.221